Wayne Harris was 35 years old when he challenged Stephane Ouellet on February 15, 2000 in Montreal, Canada. Ouellet, a former Canadian and Continental of Americas middleweight champion, won the bout by TKO after referee Gerry Bolen called a halt with one second remaining in the sixth round.The fight was scheduled for eight rounds. The defeat started a downward plunge for Harris who lost the next seven encounters over a five year period. Harris came from a family of boxers.
His younger brother Vivian remains the youngest Guyanese male to have won a world title. The elder Harris started fighting in the professional ranks in December 1984 and his career would end 22 years later.
The Pisces born fighter won the World Boxing Council (WBC) FECARBOX middleweight title on December 15, 1990 with a points decision victory over Trinidadian Anthony Brown. Harris would challenge WBA middleweight champion American Reggie Johnson on May 4, 1993 but gave a lacklustre performance and was defeated via unanimous decision.