WAYNE Harris came from a family of boxers. His younger brother Vivian remains the youngest Guyanese male to have won a world title. The elder Harris started fighting in the professional ranks in December 1984 and his career ended 22 years later. 

On February 14, 1988 Harris, then a junior middleweight, took care of fellow Guyanese Ray Alberts in a ten-round match held in Georgetown. Harris was ahead on all the judges’ card when the bell rang for the last time.
The Pisces-born fighter won the World Boxing Council (WBC) FECARBOX middleweight title on December 15, 1990 with a points-decision victory over Trinidadian Anthony Brown. Harris challenged WBA middleweight champion American Reggie Johnson on May 4, 1993 but gave a lacklustre performance and was defeated via unanimous decision.
Judge Harmodio Cedeno scored it 120-109, Oscar Perez Carbonell (120-108) and Marco Antonio Rodriguez (120-110). Harris thereafter slumped into defeat mode and had only one victory in his next 17 fights. He permanently left the ring in 2006.